Vasculitis

1. What is polyarteritis nodosa?
2. What is temporal arteritis?
*3. What is polymyalgia rheumatica?
4. What is Wegener's granulomatosis?
5. What organs does Goodpasture's disease involve?

Answers:
1. Systemic necrotizing vasculitis with palpable purpura and arthritis, in which glomerulonephritis is the leading cause of death.
2. Involves tenderness of scalp, abrupt vision loss, and is treated with high dose steroids.
3. Possibly a form of giant cell arteritis, involving fever, wt loss, malaise. It affects proximal muscles, myalgias, arthralgia. Diagnosis by elev ESR, treated with steroids.
4. Small artery involvement, "saddle-nose" deformity. Necrotizing granulomatous vasculitis involves respiratory tract and glomerulonephritis.
5. Pulmonary and kidney involvement.