Enteropathic arthropathy

1. What is enteropathic arthropathy and what is its frequency?
*2. What are the clinical joint manifestations of enteropathic arthropathy?
3. What are the extra-articular manifestations?
4. What are the lab findings of enteropathic arthropathy?

Answers:
1. Arthritis 2/2 inflammatory bowel disease (Crohn's, UC), occuring in 10-20% of those with IBD.
2. Asymmetric, involving large joints (knees, ankles, feet), sacroiliitis.
3. Erythema nodosa (Crohn's), pyoderma gangraenosa (UC), deep oral ulcers, uveitis, fever, wt loss.
4. Anemia, elev ESR/CRP, RF-, ANA-, pos anti-neutrophil cytoplasmic ab, incr HLA-B27.