Saturday, November 22, 2008

Repetitive nerve stimulation

1. What muscles are stimulated in repetitive stim?
2. What decrease in amplitude is significant?
3. What rate is used for low rate repetitive stim (LRRS)?
4. What happens if the safety factor is decreased in LRRS?
5. What is the amplitude change for LRRS in MG, LEMS, and botulism.

Answers:
1. ADM/APB, deltoid, trapezius, orbicularis oculi.
2. Greater than 10% decrease from 1st to 5th waveform.
3. 2-3 Hz.
4. Each stimulus causes the EPP amplitude to drop, so a reduced safety factor will result in the potential falling below the threshold for activation --> reduced MUAP amplitude.
5. All three disorders result in a >10% drop in amplitude.

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