1. What are the demyelinating polyneuropathies?
2. What are the axonal polyneuropathies? Of these, which have sensory and which have motor findings?
3. What polyneuropathies have both demyelination and axonal loss?
Answers:
1. HMSN-I, III, IV (e.g. Charcot-Marie-Tooth), leukodystrophy, AIDP, CIDP, arsenic, toxins, monoclonal gammopathy, diphtheria, AIDS, leprosy, Lyme disease.
2. Motor: porphyria, vincristine, lead, Dapsone, HMSN-II. Sensory: cisplatinum, Freidreich's ataxia, HSN, Sjogren's, pyridoxine, Crohn's. Sensorimotor: amyloidosis, EtOH, Vit B12, folate, toxins, gold, mercury, paraneoplastic syndrome, sarcoid, Lyme, HIV.
3. DM, uremia.
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