1.  How does tentorial (uncal) herniation occur? 
2.  What symptoms are produced from uncal herniation?
3.  Why does post-TBI HTN occur?
4.  What is the recommended treatment for post-TBI HTN?
Answers:
1.  The medial part of one temporal lobe (uncus and parahippocampal gyrus) is displaced over the edge of the ipsilateral tentorium cerebelli as a result of increased supratentorial pressure from hematoma or brain tumor.
2.  Stretching of CN III causes ipsilateral pupil dilation or third nerve palsy; ipsilateral hemiparesis from pressure on corticospinal tract; contralateral hemiparesis due to pressure on precentral motor cortex or internal capsule; late reduced consciousness.
3.  Sympathetic hyperactivity, demonstrated by increased plasma and urine catecholamines.
4.  Propranolol.
Thursday, May 15, 2008
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