Saturday, December 18, 2010

Musculoskeletal 6

What are the risks and benefits of steroid injection for lateral epicondylitis?
• Only minor complications reported: 10% postinjection pain, 2% skin atrophy, skin depigmentation, localized erythema, facial flushing
• Post-injection exacerbation lasts < 4 days
• Multiple injections may be a risk for tendon rupture
• Lit review concluded that injections associated with improved pain and grip strength in short term (<6 weeks)
• Botox has shown mixed results

What are the risks and benefits of steroid injection for de Quervain’s tenosynovitis?
• Pooled analysis recently showed symptomatic cure was established in 83% of wrists that received injection alone with low risk of complications
• Side effects: skin color changes, SQ fat atrophy, flare, nontender nodules, and superficial thrombophlebitis

What are the risks and benefits of steroid injection for carpal tunnel syndrome?
• Inject just ulnar to Palmaris longus tendon at wrist into ulnar bursa
• Meta-analysis showed steroid injection had benefit over placebo or oral steroids at 1 month
• RCT showed local steroids better than surgical decompression at 3 months and equal at 1 year
• Median nerve latencies may improve with injection, even at 12 months
• Intracarpal insulin injections may be effective in patients with NIDDM

What are the risks and benefits of steroid injection for Achilles tendonitis?
• No definitive consensus regarding benefits and risks
• 1% incidence of side effects
• No rigorous studies evaluating risk of Achilles rupture
• Weak benefit from NSAIDs
• Studies have shown no real benefit of injection

What are the risks and benefits of steroid injection for persistent plantar fasciitis?
• 80-90% of patients respond to nonsurgical treatment of plantar fasciitis
• Injections found to be more effective than extracorporeal shockwave therapy
• Posterior tibial nerve block may prevent injection pain
• Risk of rupture difficult to determine --> one study showed correlation
• Plantar fat pad necrosis may be another complication of injection

Wednesday, December 15, 2010

Musculoskeletal 5

What is the DDx and procedural management for a worker with LBP and leg pain in which conservative treatment has failed?
• Rule out systemic disease: cancer, rheum
• DDx: lumbar disc herniation, SI joint pain, facet pain, diskogenic pain, piriformis syndrome, spondylolisthesis, lumbosacral plexopathy, and lumbar spinal stenosis
• Facet pain: makes up 15-40% LBP patients. Intraarticular facet blocks can be therapeutic and diagnostic. For pure diagnosis, can do an anesthic block of the medial branches of the dorsal rami. If beneficial, can consider radiofrequency ablation.
• SI joint pain: 18-30% chronic LBP. Intraarticular SI joint steroid injections are controversial.
• ESI not proven well by studies
What are the biomechanical changes and treatment recommendations for a 40 year old dockworker diagnosed with lumbar disk herniation?
• Natural history favorable for spontaneous improvement
• At 10 year follow up, surgical group did similar to conservative group
• Caudal and intralaminar injections provide easy access to epidural space, although studies show 1/3 of blind injections do not access epidural space
• Transforaminal ESI delivers meds to anterior epidural space where nerve root traverse, always done with fluoro, may help patients reduce pain and avoid surgery

What is the efficacy of interventional procedures in diagnosis and treatment of posterior element pain in a patient with predominant LBP?
• Posterior elements: facet joints, SI joints
• Criteria that increase likelihood of facet pain: age > 65, pain relieved with recumbency, no pain exacerbation with coughing, sneezing, forward flexion, hyperextension.
• Facet pain may refer to lower back and hip
• Medial branch blocks can be diagnostic and therapeutic
• Intraarticular facet injections have been validated as an effective treatment, but limited long term efficacy
• Radiofrequency ablation of the medial branch effective in 85% of patients who responded to anesthetic block --> nerve regenerates in 90 days, no associated weakness
• SI joint: true joint with 2-3 ml of synovial fluid --> pain from trauma, sheer forces, ankylosing spondylitis, pregnancy, idiopathic
• Pain maps of SI joint intersect with facet and radic pain
• Intraartic injection of steroid and anesthetic is common treatment --> can get relief up to a year

What further diagnosis and treatment should be done on a 40 year old with disk degeneration, LBP, and referred leg pain if conservative management has failed?
• In pts with chronic LBP, prevalence of diskogenic pain is 40%
• High intensity zone on MRI within intervertebral disk may reflect annular tear, although also present in asymptomatic patients
• Diskography: performed at 3 levels in L-spine to provide at least 1 control. Procedure is painful and risks include nerve injury, diskitis, and epidural abscess --> may identify painful disk but limited value in predicting success in surgical fusion
• Intradiskal electrothermal annuloplasty: heating element catheter applied to annulus --> used on patients with axial pain and sitting intolerance >6 months with 50% preservation of disk height --> about 50% of patients have good relief, but mixed studies
• Percutaneous nucleoplasty: uses radiofrequency energy to break down molecular structures in the nucleus pulposus --> may cause disk to shrink --> not much literature to support
• Disk arthroplasty: completely replacement of disk --> new, little data

Monday, December 13, 2010

Musculoskeletal 4

How can facet injections and Botox be used to treat a worker with upper thoracic and neck pain related to whiplash injury, with failure of conservative treatment?
• Trigger point injections commonly used for whiplash, with pain relief for 1-3 weeks
• Hypotheses behind trigger point injections: MEPPs at trigger points, uncontrolled ACh release resulting in chronic muscle fiber contraction (--> Botox useful?)
• Cervical facet pain estimated to be present in 25% of neck pain patients and 50% whiplash injuries (most often C2-3 and C5-6)
• Facet pain suggested by neck pain with cervical extension and rotation, but history and physical alone are unreliable --> can do medial branch block as diagnostic tool
• Advantages of medial branch blocks: safer than intra-articular blocks, technically easier to perform
• Radiofreq neuroablation: safe and effective --> 70% response rate for cervical facet pain when performed after diagnostic block
• Medial branch of dorsal ramus regenerates in 90 days but relief may last 7-9 months
• Pulsed radiofreq ablation investigated --> lower levels of heating and lower risk of deafferentation pain --> few trials

After failure of Botox and facet injections in the above patient, who is now having neck, shoulder, and arm pain, what are other possible interventions?
• Cervical transforaminal ESI has shown promising results for clear-cut cervical radiculopathy
• Complications of cervical ESI: infection, nerve root injury, vertebral artery dissection, paralysis, stroke, high spinal block
• Interlaminar ESI may provide less availability of steroid anteriorly, but has less risk of inadvertent arterial particulate steroid deposition --> complication rate of 16.8% although most are minor
• Cervical transforaminal injection should be performed under live fluoro to avoid intravascular injection

Friday, December 10, 2010

Musculoskeletal 3

What is the efficacy of modalities and splinting in plantar heel pain?
• Limited evidence that stretching exercises and heel pads associated with better outcome than orthoses for people who stand > 8 hrs/day
• Limited evidence that topical steroids with iontophoresis would be helpful
• Limited evidence that dorsiflexion night splints reduce heel pain
• For plantar fasciitis, study showed non-WB stretching of plantar fascia better than WB stretching of Achilles --> prefabricated soft insoles and 3 weeks of NSAIDs also helpful

What is the utility of soft cervical collar and modalities for neck pain following rear-end auto collision?
• Recent study showed no utility of soft collar for pain, ROM, ADLs
• People with soft collar took longer to return to work than those treated with early mobilization
• Lack of evidence for: thermotherapy, massage, EMG biofeedback, mech cervical traction, US, e-stim

What is the utility of counterforce bracing, modalities, and exercise in a secretary with lateral epicondylitis?
• Counterforce brace: nonelastic strap curved for better fit and support of forearm, decreases muscle force on lat epicondyle --> mixed evidence for splinting
• Isotonic eccentric exercise program found to be more effective than stretching program
• Lack of evidence for modalities
• 83% of cases improved overall --> poor improvement assoc with manual jobs, high baseline pain, neuropathic sx, keyboarding, highly repetitive monotonous work

What is the utility of bracing, modalities, and exercise in assembly worker with CTS?
• Mod effectiveness for short term oral steroids
• Limited evidence for US, yoga, carpal bone mobilization
• Benefit seen from 6 weeks of nocturnal splinting, greater benefit when splints worn full time

What is the utility of lumbosacral supports and directional-based exercises for LBP?
• Moderate evidence that LS support is ineffective for primary LBP
• No evidence that support useful for secondary LBP prevention
• RCT showed McKenzie method and intensive dynamic strength training equally effective
• Study showed that patients who received direction-specific exercises (in those who had a directional preference identified) had greater improvement than non-direction-specific

What is the evidence for modalities and exercise for Achilles tendonosis?
• Weak evidence of benefit from oral NSAIDs
• Weak or no evidence for heel pads, topical laser therapy, heparin, steroid injection, modalities
• Eccentrically loading the Achilles tendon via calf muscle training is a well-supported treatment

Wednesday, December 8, 2010

Musculoskeletal 2

In a patient who was rear-ended and experienced immediate neck pain with decreased ROM but no focal neurologic problems, what is the usefulness of muscle relaxants in getting the patient back to work as a transportation worker?

• Side effects: all cause significant drowsiness, do not drive or operate heavy machinery, use with caution in patients with liver/kidney disease
• Baclofen (GABA-agonist) and tizanidine (a2-agonist) approved for spasticity and sometimes used for msk pain
• Metaxalone (Skelaxin): low side effects, no sedation, some double blind placebo studies showing positive effects of reducing back pain
• Cyclobenzaprine: structurally similar to TCAs, sedation, anticholinergic effects, more effective when used in combo with NSAIDs
• Carisoprodol (Soma): sedation, no reproducible benefits, reports of abuse and impaired driving


How can NSAIDs be used to treat the above patient?


• NSAIDs work by inhibiting COX-2 activity
• Side effects: GI bleeding, renal dysfunction, platelet inhibition, cardiovascular effects
• Celecoxib: COX-2 specific
• Meloxicam and etodolac: COX-2 selective


What is a medication treatment algorithm for acute pain in a worker who fell off a ladder, injuring his foot and ankle?


• Tylenol: has equivalent analgesia to NSAIDs for ortho injuries, liver toxicity
• Ibuprofen 800-1200mg per day has excellent safety profile --> higher dose associated with more side effects
• Opioids can be used for acute mod-severe pain, more effective with Tylenol
• Codeine metab by cyt P450, which is lacking in 10% of whites --> poor efficacy
• Tramadol: central analgesic with low affinity for opioid receptors, inhib NE and serotonin reuptake, less likely to lead to dependence


What is the rationale for use of topical analgesics to treat lateral epicondylitis in a 50 year old secretary?


• Topical meds: high concentration in dermis, muscle, and penetration into synovial fluid, can have local cutaneous reaction
• No studies to address topical opioids for acute msk pain
• Capsaicin: induces analgesia via desensitization from substance P and activates vanilloid receptors --> benefits in postherpetic neuralgia, trigem neuralgia, cluster HA, OA, not useful for acute pain
• Lidoderm: more evidence in chronic pain

Tuesday, December 7, 2010

Musculoskeletal 1

What is the diagnostic approach to a warehouse worker who develops heel pain within several weeks of starting a job that involves prolonged walking and standing on concrete floors?

• Midfoot: navicular, cuboid, and 3 cuneiform bones
• Hindfoot: talus and calcaneus
• Major soft tissue regions: calcaneal fat pad, plantar fascia, Achilles insertion
• Tendons under medial flexor retinaculum: PT, FDL, FHL
• Tendons under lateral retinaculum: peroneal tendons
• Plantar fasciitis: most common 40-70 yrs, in runners, obese. 90% of patients achieve resolution w/o surgery. Pain loc in anteromedial or central heel, gradual onset, exacerbated by toe walking, worse in AM. History may include change in footwear. Risks include pes cavus/planus, decr subtalar motion, and a tight Achilles tendon. PE shows limited ankle DF with max tenderness at anteromedial aspect of inf heel, palpate for gap (sign of rupture)
• Imaging: limited role, used to assess for calcaneal stress fx or other bony lesion. Heel spur is often noted, but of no value. Bone scan if stress fx suspected. MRI can be used for suspected AVN. Ultrasound rarely used.
• DDx: fracture, infection, malignancy, rheum d/o.
• Calcanial stress fx: 2nd most common stress fx in foot, after metatarsals. Vague pain worsens with WB. Calcaneal squeeze may reproduce pain. Plain rads may be normal initially.
• Heel fat pad atrophy: similar sx to plantar fasciitis but more diffuse, commonly in elderly. Pain does not radiate anteriorly or worsen with toe DF and is not worse in AM.
• Achilles tendonitis: from overuse, jumping, running.
• Retrocalcaneal bursitis: Achilles tendon insertional pain, caused by abrasion and resulting in inflammation of the burse between the Achilles insertion and the calcaneus, from shoes. Associated with Haglund’s disease, bony protuberance of calc tuberosity.
• Peroneal tendon ruptures occur prox to insertion or just distal to lat malleolus, associated with swelling and tenderness after multiple ankle sprains
• Tarsal tunnel: numbness, tingling or burning pain, worsened with prolonged WBing and ambulation. Foot DF and eversion stretches nerve and can reproduce symptoms
• Other causes of neurogenic heel pain: medial calcaneal neuroma, S1 radic, neuropathy of nerve to abductor digiti quinti.



What is the diagnostic assessment of a transportation worker who p/w neck pain after a rear end collision while stopped at the side of the road?


• Most people involved in collisions have symptoms resolve in 4-6 weeks, but up to 1/3 have chronic symptoms
• Symptoms assoc with whiplash: neck pain and stiffness, arm pain, paresthesias, TMJ, HA, dizziness, visual disturbance, difficulty with memory/concentration
• Controlled diagnostic blocks show facet pain generators in 60% of patients
• Center of headrest should be at ear level and not reclined
• Symptoms may be mild after the accident but increase in the following 2-3 days
• Neurologic deficits are rare
• Imaging: flexion and extension films to r/o instability, plain rad may show decr lodosis. MRI usually unnecessary


What is the pathogenesis of job-related wrist and elbow pain?


• Risks: old age, obesity, DM, smoking, pregnancy, rheum arthritis, psych stress
• History should assess high repetitive nature of work and prolonged abnormal postures, pain at insertion of muscle or tendon
• Tx: PT/OT with work modifications
• DeQuervain’s: pain in 1st dorsal compartment (APL, EPB). Finkelstein’s test positive.
• CTS: pain, numbness, and tingling in first three digits


What is a diagnostic plan for a loading dock worker with LBP?


• History: determine if injury related to work, possible litigation
• Exclude fx, infection, cauda equina syndrome (ask about B/B symptoms). Ask about cancer history, IV drug use, fever, night sweats
• PE: Assess symmetry of muscle bulk and tone, kyphosis or lordosis, scoliosis, L-spine ROM to flexion, ext, bending and rotation. Strength testing, sensation, reflexes. Peripheral pulses.
• Schober’s test: line drawn between PSIS at S2 and draw line to 5 cm below and 10 cm above. And increase of more than 5 cm is normal.
• Check hamstring and gluteus maximus flexibility: Ely test, Thomas test
• Femoral stretch test: L4 nerve root pathology
• SLR: positive if pain below knee at 30-70 degrees of hip flexion
• SIJ pain: No tests sensitive or specific. FABER test, Gaenslen test, Gillet test.
• 5 Waddell signs: nonanatomic regional tenderness, overreaction, nonanatomic regionalization, distraction, and simulation (axial loading)  3/5 must be positive
• If no red flags, imaging may not be necessary
• Early X-rays if: age > 50, significant trauma, neurologic deficits, unplanned wt loss, assess ank spondylosis, drug/alcohol abuse, cancer history, steroid use, fever, no improvement with conservative care, pain > 7 weeks
• CT useful for assessing bones: foraminal bony narrowing and lateral recess stenosis, assess for fx if pt cannot get MRI
• MRI: useful for bone and soft-tissues, disk degen, endplate changes, neoplastic conditions. Gad contrast helps detect fracture, neoplasms, demyelination.
• 35% prevalence of DDD in young people < 40, 100% in age > 60yrs. 36% prev of herniated disk in >60 yrs.
• Bone scans for neoplasm or infection
• EMG to ID objective weakness, r/o neuropathy or neuromusc disease, localize lesion, assist in prognosis

Wednesday, August 18, 2010

test

this is a test